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Microplastics found in human blood for the first time

A Dutch pilot study detected plastic particles in the blood of 17 of 22 healthy adults, at an average of 1.6 micrograms per millilitre.

Authors / organisation
Leslie H.A., van Velzen M.J.M., Brandsma S.H., Vethaak A.D., Garcia-Vallejo J.J., Lamoree M.H.
Year
2022
Journal or publisher
Environment International
Digital object identifier (DOI)
10.1016/j.envint.2022.107199
Study type
Cross-sectional
Evidence strength
Evidence: Medium
Sample / scope
22 healthy adult volunteers (Netherlands)
Key finding
Plastic particles were quantified in the blood of 17 of 22 healthy adults (77%), mean 1.6 µg/mL, mostly PET, polyethylene and polystyrene.
Headline number
77% of people tested had plastic in their blood
Caveats / how it is misquoted
Small pilot study; no health outcomes measured.
Open access
Yes
Verified on
22 September 2026

Researchers at Vrije Universiteit Amsterdam developed a method to detect and measure plastic particles as small as 700 nanometres in whole blood, then applied it to samples from 22 healthy adult volunteers.

Plastic was quantified in 17 of the 22 people (77%), with an average concentration of 1.6 micrograms per millilitre. PET (used in drink bottles), polyethylene (bags and packaging) and polystyrene were the most common polymers.

This was the first proof that plastic particles circulate in the human bloodstream and can therefore reach organs. It opened the door to the wave of studies that followed on placenta, brain, heart and other tissues.

It was a small pilot study, described by its own authors as pioneering. It says nothing about health effects, and the concentration figure should not be extrapolated to the population.

Sources last verified 22 September 2026. Page updated 22 September 2026. How we check sources